Article: Peginterferon alfa-2b (PegIntron) has to be given twice weekly, authors note in study.

Vienna, Austria, July 28 /PRNewswire/ -- A study published in the July issue of the Journal of Viral Hepatitis(i) shows that the currently prescribed once weekly dosing schedule of peginterferon alfa-2b (PegIntron(tm)-Schering-Plough) does not provide sustained suppression of the hepatitis C virus (HCV). The study found that to achieve continuous drug exposure and to improve viral clearance, peginterferon alfa-2b has to be given at least twice weekly.

The study, conducted at the University of Vienna, investigated whether twice weekly dosing of PegIntron(tm) improves viral kinetics over once weekly dosing. Twenty interferon-naE[macron]ve patients with chronic ...

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