Article: Twice-weekly administration of peginterferon-alpha-2b improves viral kinetics.

2003 AUG 18 - (NewsRx.com & NewsRx.net) -- University of Vienna internists are recommending at least twice-weekly dosing of peginterferon-alpha-2b for their patients with chronic hepatitis C.

They say this schedule is necessary to continually expose the virus to the drug and to improve initial viral clearance.

"The decline in hepatitis C viral load on treatment with peginterferon-alpha-2b is not continuous," said E. Formann and colleagues. "The aim of this study was to investigate whether twice weekly dosing of peginterferon-alpha-2b [PEG-IFN-a-2b] may improve viral kinetics."

Study subjects were 10 interferon-naive patients with chronic ...

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