Article: Systemic contact dermatitis to doxepin. (Case Reports).

Abstract

Although allergic contact dermatitis to topical preparations of doxepin has been published (1-6, 10), systemic contact dermatitis from oral doxepin is more of a theoretical consideration and is rarely reported (2). We report a case of a patient with contact allergy to doxepin hydrochloride 5% cream who developed a systemic contact dermatitis to oral doxepin.

Case Report

A 75-year-old retired man was referred for evaluation of a chronic pruritic dermatitis of one year's duration on his scalp, axillae, trunk, lower legs, and feet. His eruption had been resistant to treatment by various medications. These included oral antihistamines, ...

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