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Article: Cyclosporin can cause lip hypertrophy; change to tacrolimus resolves it.
- Article from:
- Drug Week
- Article date:
- August 29, 2003
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2003 AUG 29 - (NewsRx.com & NewsRx.net) -- Following transplant, immunosuppression with cyclosporin can cause lip hypertrophy; change to tacrolimus resolves it.
According to a study from England, "Gingival hypertrophy is a well documented side effect of cyclosporin therapy, but severe lip enlargement is less frequently recognized. This can lead to poor body image, low self-esteem and noncompliance, especially in the older childhood and adolescent age groups.
"We describe two pediatric renal transplant recipients who had marked lip hypertrophy as a consequence of cyclosporin (Neoral) treatment. On changing immunosuppression to tacrolimus (Prograf), it ...