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Article: Novel selection method improves isolation of murine embryonic stem cells.
- Article from:
- Biotech Week
- Article date:
- September 10, 2003
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2003 SEP 10 - (NewsRx.com & NewsRx.net) -- A novel selection method enables the isolation of embryonic stem (ES) cells from previously resistant murine strains.
Isolation of murine ES cells "has been almost exclusively from the 129 mouse strain," scientists in Scotland explained. "Other mouse strains, such as CBA, have proven refractory to ES cell isolation by conventional means."
"We previously reported the isolation of 87.5% CBA ES lines by selective ablation of differentiating cells (McWhir et al., 1996)," noted E.J. Gallagher and coauthors at the Roslin Institute.
In their subsequent study, the investigators achieved "the isolation of ES ...