Article: FOSAMAX Increased Bone Mineral Density Twice As Much as Evista.

Business Editors/Health & Pharmaceutical Writers

MINNEAPOLIS--(BUSINESS WIRE)--Sept. 22, 2003

Merck & Co., Inc. (NYSE:MRK)

FOSAMAX and Evista Demonstrated Similar Upper GI Safety and Overall

Tolerability Profiles in Two Head-to-Head Studies Presented at ASBMR

In one-year head-to-head trials comparing FOSAMAX(R)(alendronate sodium) once-weekly, the most prescribed medicine(1) for osteoporosis treatment, to Evista, FOSAMAX 70 mg provided significantly greater increases in bone mineral density (BMD) at one-year at the lumbar spine and total hip compared to Evista (raloxifene) 60 mg once-daily. Findings from these two studies, one ...

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