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Article: Analysis of nuclear-cytoplasmic translocation using high throughput microscopy: real-time investigation of cellular and sub-cellular processes.(Tools & Techniques)
- Article from:
- Bioscience Technology
- Article date:
- August 1, 2003
- Author:
CopyrightCOPYRIGHT 2003 Advantage Business Media. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
It is increasingly recognized that gaining a detailed understanding of complex biological systems such as cellular pathways is fundamental to advances in basic research and drag discovery. Most importantly, there is a need for the direct visualization of complex cellular and sub-cellular processes that serve to improve early drug discovery and basic research. The EIDAQ[TM] 100 HTM cellular imaging and analysis system facilitates accurate investigation of cellular and sub-cellular processes in real time. Here we describe how image analysis using the system is applied to quantify intracellular translocation of the transcription factor NF-[kappa]B. ...
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