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Article: Treatment interruption: study found poor result for highly treated, highly resistant patients.
- Article from:
- AIDS Treatment News
- Article date:
- September 12, 2003
- Author:
CopyrightCOPYRIGHT 2003 John S. James. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Patients whose antiretroviral treatment was no longer working well due to extensive drug resistance were randomly assigned to two different groups. In one, the control group, they changed their treatment immediately to a new antiretroviral regimen devised by their doctor with the help of viral resistance testing. In the other, the treatment-interruption group, patients also changed their treatment based on resistance testing, but first they went off all antiretrovirals for four months. The idea was to see if the virus would partly revert to more drug-sensitive strains during the treatment interruption, in the hope that the drugs would work better later when they were ...