|
|
Article: Poloxamer-containing liposomes can be used for heat-sensitive drug delivery.
- Article from:
- Gastroenterology Week
- Article date:
- October 6, 2003
CopyrightCOPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Poloxamer-containing liposomes as a heat-sensitive drug delivery system in vivo for colon tumors.
According to published research from the United States, "A heat-sensitive liposomal drug delivery system was tested using Colon-26 (CT-26) cultured cells and tumors in mice.
"Lucifer yellow iodoacetamide (LY) was used as a fluorescence marker. The heat-sensitive liposomes exploit the temperature-dependence of critical micellar concentrations of the poloxamer, F127. LY release from unilamellar liposomes at different temperatures was measured," wrote J. Wells and colleagues, Roswell Park Cancer Institute, Molecular & ...