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Article: Beta-arrestin-2 regulates the development of allergic asthma.
- Article from:
- Drug Week
- Article date:
- October 24, 2003
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2003 OCT 24 - (NewsRx.com & NewsRx.net) -- Beta-arrestin-2 regulates the development of allergic asthma.
According to recent research published in the Journal of Clinical Investigation, "Asthma is a chronic inflammatory disorder of the airways that is coordinated by Th2 cells in both human asthmatics and animal models of allergic asthma. Migration of Th2 cells to the lung is key to their inflammatory function and is regulated in large part by chemokine receptors, members of the seven-membrane-spanning receptor family. It has been reported recently that T cells lacking beta-arrestin-2, a G protein-coupled receptor regulatory protein, demonstrate impaired migration ...