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Article: Zic2 plays key role in binocular vision.
- Article from:
- Genomics & Genetics Weekly
- Article date:
- October 31, 2003
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2003 OCT 31 - (NewsRx.com & NewsRx.net) -- The transcription factor Zic2 plays a key role in the development of binocular vision.
"During CNS development, combinatorial expression of transcription factors controls neuronal subtype identity and subsequent axonal trajectory," scientists in New York explained. However, "regulatory genes designating the routing of retinal ganglion cell (RGC) axons at the optic chiasm to the appropriate hemisphere, a pattern critical for proper binocular vision, have not been identified."
In their study, E. Herrera and colleagues at Columbia University found that "the zinc finger transcription factor Zic2, a vertebrate ...