Article: HSV-2 underrecognized in HIV-positive patients: subclinical infection.(Gynecology)

OTTAWA--Herpes simplex virus type 2 infection is prevalent--and largely unrecognized--among HIV-positive patients.

Epidemiologists have recognized for two decades that the presence of genital ulcers heightens the risk for transmission of HIV. But it is now known that even asymptomatic HSV-2 infection can increase HIV transmissibility.

"Both subclinical and clinical HSV-2 reactivation increase the frequency and amount of mucosal HIV-1 shedding," Dr. Jennifer L. Meyer said at a congress of the International Society for Sexually Transmitted Diseases Research.

In a survey of 246 patients at a Seattle HIV clinic, 172 (70%) were HSV-2 seropositive; ...

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