Article: Once Daily Fondaparinux Found as Effective and Safe as Unfractionated Heparin In the Initial Treatment of Symptomatic Pulmonary Embolism; Published Report of MATISSE PE Study in the New England Journal of Medicine Sets Stage for Improved Management of Patients Suffering From the Condition.

AMSTERDAM, Netherlands, Oct. 29 /PRNewswire/ -- Once daily subcutaneous administration of the synthetic, selective factor Xa inhibitor fondaparinux (Arixtra(R)) is at least as effective and safe as intravenous unfractionated heparin (UFH) in the initial treatment of patients with symptomatic pulmonary embolism (PE) according to the MATISSE PE study published today in the New England Journal of Medicine.

"After 50 years of using unfractionated heparin in acute antithrombotic therapy, the MATISSE PE study shows that pulmonary embolism can now be treated with an agent that can be administered subcutaneously immediately upon diagnosis with no need for monitoring or ...

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