|
|
Article: PAMPA possibilities: high-throughput automation of the Parallel Artificial Membrane Permeation Assay.(Feature)
- Article from:
- Chemistry and Industry
- Article date:
- October 20, 2003
- Author:
CopyrightCOPYRIGHT 2003 Society of Chemical Industry. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
In pharmaceutical ADME (Absorption, Distribution, Metabolism and Excretion) departments it is important to know how well a drug will be absorbed into the body. Orally administered drugs will generally rely on transfer into the bloodstream through the wall of the small intestine. Various reproducible techniques have been developed for in-vitro measurements of how well a drug will pass through the intestinal lining, and the best known of these is the Caco-2 assay, which relies on the use of a cell line that originated from a single source of human colon cells.
However, the Caco-2 assay is not all things to all men and for a variety of reasons is not favoured or ...
Related newspaper, magazine, and journal articles:
|
|
Article: pampas
The Columbia Encyclopedia, Sixth Edition;
609 words
...pampas , wide, flat, grassy plains ... rainfall received, the soil of the pampas is very fertile and supports ... pastoral and farming economy. The Pampa, c.250,000 sq mi (647 ... Córdoba, and La Pampa. Cattle was first introduced ...
|
|