Article: Short trinucleotide repeat genotypes of AR gene protect against breast cancer.

2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Short trinucleotide repeat genotypes of the AR gene protect against breast cancer.

"Up to one-third of women with breast cancer have a family history of breast cancer, and approximately 5% of cases are attributed to mutations in high-risk breast cancer susceptibility genes, such as BRCA1 and BRCA2," scientists writing in the journal Cancer Epidemiology Biomarkers & Prevention report.

"It is believed that genes of lower penetrance, but of greater prevalence, may also modulate a woman's risk of breast cancer. We studied the association of breast cancer and the trinucleotide repeat polymorphism, (CAG(n)) in exon 1 ...

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