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Article: Lymphotoxin beta receptor is involved in gut autoimmunity, inflammation, IgA.
- Article from:
- Immunotherapy Weekly
- Article date:
- November 19, 2003
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2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Lymphotoxin beta receptor appears to be a key target in the gut for control of autoimmunity and inflammation and for increasing the protective IgA response.
According to published research from the United States, "Signaling through lymphotoxin beta receptor (LTbetaR) initiates the unfolding of a host of developmental programs ranging from the organogenesis of lymph nodes and Peyer patches (PPs) to the coordination of splenic microarchitecture.
"While investigating an alternative pathway to immunoglobulin A (IgA) production, it was uncovered that LTbetaR signaling in the lamina propria (LP) stroma orchestrates ...