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Article: A practical technique for differentiation of sub-epidermal bullous diseases: localization of in vivo-bound IGG by laser scanning confocal microscopy.(Washington Whispers)(Brief Article)
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- October 1, 2003
- Author:
CopyrightCOPYRIGHT 2003 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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The purpose of this study was to develop a practical technique to distinguish autoimmune sub-epidermal bullous diseases.The authors present a prospective study from an academic referral center. The patient population consisted of forty-two patients fulfilling clinical, immunological, and/or immunoelectron microscopic criteria for bullous pemphigoid (n = 31), mucous membrane pemphigoid (n = 6), or epidermolysis bullosa acquisita (n = 5), diagnosed as having disease and treated from January 1, 1997, to December 31, 2002. Laser scanning confocal microscopy was applied to determine the localization of in vivo-bound IgG at the basement membrane zone in biopsy specimens taken ...