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Article: Reassessment of combining benzoyl peroxide with clindamycin.(Letters To The Editor)(Letter to the Editor)
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- December 1, 2002
- Author:
CopyrightCOPYRIGHT 2002 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Dear Dr. Robins:
I was most interested in the article by Tschen and Jones concerning the clinical and antimicrobial results of the topical combination product containing clindamycin and benzoyl peroxide (1). Previous publications have also revealed the mixture of topical antibiotics and benzoyl peroxide diminishes the multiplication of antibiotic-resistant strains (2). Such combination therapies are hypothesized to gain their efficacy by the coupled action of two effective acne treatments. Of note, there has been a dearth of chemical data proving any synergistic activity with such a combination.
In the laboratory, I have compared the radical activity of ...