Article: Borrelia burgdorferi induces inflammatory cytokines during erythema migrans.

2003 DEC 1 - (NewsRx.com & NewsRx.net) -- Inflammatory cytokines are induced in PBMC of newly infected patients with erythema migrans from Borrelia burgdorferi.

According to recent research from the United States, "in a study of cytokine production ex vivo by Borrelia burgdorferi-stimulated peripheral blood mononuclear cells from 27 patients with culture-positive erythema migrans, production of inflammatory cytokines predominated, particularly gamma interferon (IFNgamma) and, to a lesser degree, tumor necrosis factor alpha (TNFalpha).

In contrast, with the exception of interleukin-13 (IL-13), anti-inflammatory cytokine production was negligible," wrote ...

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