Article: Immune Response licenses Hybridon's AMPLIVAX vaccine adjuvant.

The Immune Response Corporation (Carlsbad, CA) and Hybridon, Inc. (Cambridge, MA) have entered into a license agreement for the use of AMPLIVAX as an adjuvant in the development of a novel vaccine candidate for the prevention and treatment of HIV, the virus that causes AIDS. The new vaccine candidate, which has already demonstrated activity in laboratory experiments, combines the whole-killed vaccine technology employed in REMUNE, an immune-based HIV therapeutic vaccine being evaluated in Phase II clinical trials by The Immune Response Corporation, plus AMPLIVAX, Hybridon's 2nd generation immunomodulatory oligonucleotide (IMO) adjuvant designed to enhance the immune ...

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