Article: Anxiolytics the nonbenzodiazepines.(Prime for Prescription Medicines)

Besides the antidepressants and benzodiazepines described in previous "Primer of Prescription Medication" articles, there are additional medication approaches that may augment psychotherapy for anxiety disorders. The first of these we will discuss is buspirone (BuSpar[TM]). BuSpar is an azaspirone and does not directly affect the gamma-aminobutyric (GABA) system as the benzodiazepines do, nor does it block reuptake of serotonin like the antidepressants. It acts as a partial agonist at the serotonin type 1-A receptor in the brain and has minimal effects on any other organ system. It was superior to placebo and equal to the benzodiazepines against which it was tested in ...

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