Article: Alternating acetaminophen and ibuprofen in the febrile child: examination of the evidence regarding efficacy and safety.(Evidence-Based Practice)

Despite its frequently benign nature, the presence of fever in children continues to spark fear in the hearts of parents and health care practitioners alike. In fact, fever is one of the most common pediatric problems, accounting for 25%-30% of emergency department and clinic visits each year (Bachur, 2001; Murphy, 1992; Wong et al., 2001). Most pediatric specialists define fever as a rectal temperature greater than 38.0[degrees] C (100.4 F) or an oral temperature above 37.8[degrees]C (100 F) (Hay, Groothius, Hayward, & Levin, 1997). Fever can have a multitude of causes, including infections, vasculitic syndromes, central nervous system disorders, neoplasms, poisonings, ...

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