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Article: Genetic link to epilepsy after brain injury.
- Article from:
- Nutrition Health Review
- Article date:
- June 22, 2003
CopyrightCOPYRIGHT 2003 Vegetus Publications. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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People who inherit a particular gene involved in lipid metabolism in the brain appear to be at higher risk of experiencing seizures after traumatic brain injury, according to researchers at University of Texas-Southwestern Medical Center at Dallas.
A study published in Archives of Neurology (June 2003) found that patients with moderate to severe brain injuries who had inherited the epsilon 4 variation of the apolipoprotein E (apoE) gene were 2.41 times more likely to have seizures than patients without the gene.
The finding sheds new light on the pathophysiology of post-traumatic epilepsy and may lead to new therapies to prevent seizures in brain-injured ...