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Article: Amino acid profiling clinical guidelines for determination of preferred specimen choice.
- Article from:
- Townsend Letter for Doctors and Patients
- Article date:
- December 1, 2003
- Author:
CopyrightCOPYRIGHT 2003 The Townsend Letter Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Introduction
Profiling of amino acids in plasma and urine has been used to elucidate a rapidly growing number of aminoacidopathies since the introduction of partition chromatography methods in 1945. (1) The question of whether plasma or urine may be the preferred specimen choice for amino acid testing is a frequent clinical concern in the evaluation of a patient's amino acid status. An informed decision must involve what principal clinical answers are sought and which amino acids are being tested. To state categorically that profiling of amino acids is best performed on plasma or urine is to oversimplify. The question of preferred specimen can be answered only ...
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