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Article: Columbia University obtains United States patent.(Brief Article)
- Article from:
- BIOTECH Patent News
- Article date:
- December 1, 2003
CopyrightCOPYRIGHT 2003 Biotech Patent News. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Columbia University in the City of New York (New York, NY) has patented an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase. This invention provides a fusion protein comprising a PAK4 serine/threonine kinase or a fragment thereof and a second peptide. This invention provides a purified mammalian PAK4 serine/threonine kinase. This invention provides a monoclonal antibody directed to an epitope of a PAK4 serine/threonine kinase. This invention provides a method of inhibiting PAK4 function comprising administering a ...
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... ... chromosome 19p13.3 have been identified as a cause of PJS [4, 5]. The human STK11 gene encodes a 433 amino acid serine-threonine kinase. STK11 is known to be located both in the nucleus and the cytoplasm of all human tissues [6], and orthologs include ...
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