Article: BRCA mutation testing warranted in women with bilateral breast cancer, regardless of family history: 25% have deleterious mutation.(News)

SAN ANTONIO -- Women with bilateral invasive breast cancer have a high prevalence of BRCA1 and BRCA2 mutations regardless of whether they possess a strong family history of breast or ovarian cancer, Alicia A. Parlanti reported at a breast cancer symposium sponsored by the Cancer Therapy and Research Center.

Based upon this observation in a large new study, all women with bilateral invasive breast cancer--including those in whom the first and second diagnoses are separated by decades--ought to be offered genetic risk assessment services including BRCA mutation testing, said Ms. Parlanti of Myriad Genetic Laboratories in Salt Lake City.

She reported on ...

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