Article: Virulence factor identified.

2004 JAN 28 - (NewsRx.com & NewsRx.net) -- Chagas disease affects more than 18 million people in Latin America. The agent responsible is a protozoan parasite, Trypanosoma cruzi, transmitted by haematophagous insects. For survival in the host's organism, it uses several strategies, but especially one of inhibiting the host's immune response.

Research scientists from the Institute of Research for Development (IRD) and Institut National de la Sante et de la Recherche Medicale (INSERM) who are studying this trypanosome found that one of the proteins it secretes, Tc52, is a virulence factor that plays a pivotal role in the infection mechanism. Combining different ...

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