Article: An 8q24 aberration is a negative outcome predictor in NHL.

2004 JAN 26 - (NewsRx.com & NewsRx.net) -- For patients with non-Hodgkin's lymphoma (NHL), the presence of a 8q24 aberration results in a statistically significant inferior prognosis than its absence in all histological groups, researchers find.

"To define the histologic, cytogenetic (CG) and clinical spectrum of NHL carrying an 8q24 (c-myc) translocation, 87 patients with an 8q24 aberration were identified from 785 consecutive successfully analyzed cases," scientists in the People's Republic of China report.

"Aberrations involving 8q24 were found at diagnosis (n=66) or at relapse/progression (n=21). Histologically, Burkitt-like lymphoma (BLL) (32%) and ...

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