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Article: Hypoglycemic effect of Sclerocarya birrea {(A. Rich.) Hochst.} [Anacardiaceae] stem-bark aqueous extract in rats.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- November 1, 2003
- Author:
CopyrightCOPYRIGHT 2003 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Summary
This study was undertaken to evaluate the hypoglycemic effect of Sclerocarya birrea {(A. Rich.) Hochst.} subspecies caffra (Sond.) Kokwaro [family: Anacardiaceae] stem bark aqueous extract in normal (normoglycemic) and in streptozotocin (STZ)-treated, diabetic Wistar rats. In one set of experiments, graded doses of S. birrea stem-bark aqueous extract (SB, 100-800 mg/kg p.o.) were separately administered to groups of fasted normal and fasted diabetic rats. In another set of experiments, a single dose of the plant aqueous extract (SB, 800 mg/kg p.o.) was used. The hypoglycemic effect of this single dose (SB, 800 mg/kg p.o.) of S. birrea stem-bark aqueous ...