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Article: Oral cicatricial pemphigoid.(Pathology Clinic)
- Article from:
- Ear, Nose and Throat Journal
- Article date:
- January 1, 2004
- Author:
CopyrightCOPYRIGHT 2004 Vendome Group LLC. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Cicatricial pemphigoid is a vesiculobullous disease of the skin that may be found in the oral cavity. Previously designated "benign mucous membrane pemphigoid," cicatricial pemphigoid is a chronic, blistering, autoimmune disease that affects mucous membranes. Tissue-bound autoantibodies are directed against one or more components of the basement membrane in an affected individual. Cicatricial pemphigoid initially occurs in the fifth to seventh decades of life, and it is observed more frequently in women. Patients usually describe oral pain and/ or ulceration, often of many years' duration. Clinically, the disease is characterized by the formation of bullae, which can be ...