Article: Lupus nephritis may occur with crystal structures made of immunoglobulins.

2004 JAN 16 - (NewsRx.com & NewsRx.net) -- Lupus nephritis may occur with crystal structures made of immunoglobulins.

"Lupus nephritis is a common phenomenon in systemic lupus erythematosus (SLE). We analyzed a renal biopsy of a 30 yr old woman with SLE. The clinical history showed typical SLE, with generalized symptoms, without demonstrable lupus coagulant; positive for anti-nuclear antibodies and anti-ds-DNA antibodies, but negative for rheumatoid factor, cryoglobulins, and antiphospholipid antibodies," scientists in Germany report.

"A paraproteinemia for IgA, IgG, and IgM was not detectable. Using light, electron, and immunoelectron microscopy we ...

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