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Article: Marmosets infected with GB virus B are a surrogate model for HCV infection.
- Article from:
- Proteomics Weekly
- Article date:
- March 22, 2004
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2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Marmosets infected with GB virus B are a surrogate model for HCV infection.
"GB virus B (GBV-B), a flavivirus closely related to HCV, has previously been shown to infect and replicate to high titers in tamarins (Saguinus sp.). This study describes the use of GBV-B infection and replication in the common marmoset (Callithrix jacchus) for the successful development and validation of a surrogate animal model for hepatitis C virus (HCV)," investigators in England report.
"Infection of marmosets with GBV-B produced a viremia that peaked at 10[superscript]8 to 10[superscript]9 genome copies/ml for a period of 40 to 60 ...