Article: Tryptophan trips up. (dietary supplements ) (Cover Story)

In November 1989, Gerald Gleich of the Mayo Clinic placed a call to the Centers for Disease Control in Atlanta. He reported that three women in New Mexico and one person in Minnesota were suffering from the same puzzling symptoms.

All had been taking tryptophan, an amino acid the body uses to build protein.

The Disease

The new disease was called EMS, or Eosinophilia-Myalgia Syndrome, because patients have high levels of white blood cells called eosinophils and muscle pain (myalgia). What does it feel like?

"Imagine a painful cramp in the foot multiplied a hundredfold," said Paul L. Houts, an EMS victim who testified at a ...

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