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Article: Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes.(Abstracts)(Brief Article)
- Article from:
- Alternative Medicine Review
- Article date:
- March 1, 2004
- Author:
CopyrightCOPYRIGHT 2004 Thorne Research Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Cohen RA, Browndyke JN, Moser DJ, et al. Cerebrovasc Dis 2003:16:199-204.
BACKGROUND: Cytidine diphosphate choline (citicoline) has been previously shown to have efficacy in reducing the functional impairments associated with acute stroke. Citicoline is thought to have neuroprotective benefits and has been used for the treatment of chronic cerebrovascular disorders, though its effectiveness has not been fully tested. This randomized, double-blind clinical trial was conducted to determine whether daily citicoline treatment improves neurocognitive and neuroimaging outcome over 12 months among patients diagnosed with vascular dementia (VaD). METHODS: 30 patients ...
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