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Article: Transcription factor required for lamina propria differentiation.
- Article from:
- Health & Medicine Week
- Article date:
- March 29, 2004
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2004 MAR 29 - (NewsRx.com & NewsRx.net) -- Activating transcription factor 4 is required for the differentiation of the lamina propria layer of the vas deferens.
According to published research from the United States, "Activating transcription factor 4 (ATF4/CREB2) is a member of the cyclic-AMP response element-binding (CREB) family. These proteins have been shown to regulate cell proliferation and differentiation in a broad number of tissues during embryo development. Here we report that male ATF4[superscript]-/- mice are subfertile, despite the fact that they produce sufficient sperm and are able to fertilize wild-type eggs in vitro."
"An analysis of ...