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Article: Low-protein diet alters gene expression in rat pancreatic islets.
- Article from:
- Biotech Week
- Article date:
- April 7, 2004
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2004 APR 7 - (NewsRx.com & NewsRx.net) -- A low-protein diet alters gene expression in rat pancreatic islets.
"Insulin secretion is regulated mainly by circulating nutrients, particularly glucose, and is also modulated by hormonal and neuronal inputs. Nutritional alterations during fetal and early postnatal periods, induced by either low protein or energy-restricted diets, produce beta-cell dysfunction. As a consequence, insulin secretion in response to different secretagogues is reduced, as is the number of beta-cells and the size and vascularization of islets," scientists in Brazil report.
"In this study, we used a cDNA macroarray technique and RT-PCR ...