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Article: Capillary electrophoresis and the pharmaceutical industry: a new era.
- Article from:
- Canadian Chemical News
- Article date:
- September 1, 1991
- Author:
CopyrightCOPYRIGHT 1991 Chemical Institute of Canada. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Advancements in the area of drug related research have increased the demand for sophisticated analytical instrumentation and methodology. Methodologies examining chemical identity, structural confirmation, purity control and chemical activity assays have shown much progress. However, the complexity of many biomolecules, along with their respective sample environments, leaves many challenges open for further development.
To increase the confidence of results determination, two or more complementary techniques are usually required for qualitative and quantitative assays. Protein, peptide and oligonucleotide separations primarily employ HPLC and slab-gel ...