Article: Effect of short-term exposure to low levels of SO2 and NOx on pulmonary function and methacholine and allergen bronchial sensitivities in asthmatic children. (sulfur dioxide, nitrogen oxides)

CONTINUOUS EXPOSURE to low, moderate, or high air pollution may affect the development of chronic childhood respiratory allergic disease. [1] Unusually high concentrations of air pollutants (e.g., 2-5 ppm for sulfur dioxide [[SO.sub.2]]) cause acute deleterious effects on lung function. Of course these concentrations markedly exceed cncentrations commonly observed in an urban polluted atmosphere (e.g., 0.1-0.5 ppm). [2-5] Few studies have demonstrated that asthmatics might also react to a lower level (0.1-0.5 ppm) of pollutants during a prolonged exposure (i.e., 2 h). However, these conditions are not often encountered in normal daily life.

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