|
|
Article: DNA vaccine against Streptococcus mutans characterized.
- Article from:
- Drug Week
- Article date:
- May 7, 2004
CopyrightCOPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2004 MAY 7 - (NewsRx.com & NewsRx.net) -- Scientists have characterized a fusion anti-caries DNA vaccine against PAc and glucosyltransferase I of Streptococcus mutans.
"Glucosyltransferases (GTFs) and A cell-surface protein (PAc) are two important virulence of the cariogenic organism Streptococcus mutans. They may mediate sucrose-in dependent or sucrose-dependent attachment of Streptococcus mutans to tooth surfaces, respectively. Thus, inhibiting both virulence factors is predicted to provide better protection against caries than inhibiting a single factor," researchers in China report.
"To develop a highly efficient vaccine against caries, we ...