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Article: Bone marrow and stem-cell features characterized in RA patients.
- Article from:
- Hematology Week
- Article date:
- May 10, 2004
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2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Characteristic features of bone marrow and hematopoietic stem-cell populations have been identified in rheumatoid arthritis patients.
In a recent study, scientists in Italy "evaluated bone marrow morphology, percentage of bone marrow CD34+ cells, proliferative activity of bone marrow precursors, clonogenic assay (BFU- E and CFU-GM) in short-term bone marrow cultures, and bone marrow cell apoptosis, together with serum TNF-alpha and IL-6, in 16 chronic, refractory RA patients, as well as in five healthy controls.
"Of 16 RA patients (68.7%), 11 showed a reduced bone marrow cellularity, while it was normal in all ...