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Article: Multilocus sequence typing and the evolution of methicillin-resistant Staphylococcus aureus.(Molecular Epidemiology)(Brief Article)
- Article from:
- Emerging Infectious Diseases
- Article date:
- May 1, 2004
- Author:
CopyrightCOPYRIGHT 2004 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Methicillin-resistant Staphylococcus aureus (MRSA) continue to adapt to the selective pressure of antimicrobial agents and to exploit new niches, as evidenced by the recent isolation of strains with high-level vaneomycin resistance and the emergence of MRSA as a community pathogen. The combined use of the bacterial genotyping technique, multilocus sequence typing (MLST), and characterization of the mobile methicillin-resistance determinant, staphylococcal chromosomal cassette mec (SCCmec), has provided new insights into MRSA strain nomenclature, evolution, and epidcmiology. The first MRSA emerged when SCCmec was acquired by ...