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Article: T3 exposure causes myocardium hypertrophy and increased SR Ca2[superscript]+ ATPase activity.
- Article from:
- Hematology Week
- Article date:
- May 24, 2004
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2004 MAY 24 - (NewsRx.com & NewsRx.net) -- Thyroid hormone exposure causes myocardium hypertrophy and increased SR Ca2[superscript]+ ATPase activity.
"Hyperthyroidism is known to affect multiple organ functions, and thyroid hormone has been known to improve myocardial function in a failing heart. The purpose of this study is to elucidate the functional and metabolic effects of thyroid hormone on myocardium in a rat model exposed to long-term excess thyroid hormone, particularly focusing on the SIR Ca2[superscript]+-ATPase (SERCA2) function," wrote investigators in Japan.
"3,5,3'-Triiodo-L-thyronine (T3), or the vehicle, was subcutaneously given for 4 ...