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Article: IGF expression higher in tissue of women at high breast cancer risk.
- Article from:
- Immunotherapy Weekly
- Article date:
- May 26, 2004
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2004 MAY 26 - (NewsRx.com & NewsRx.net) -- Insulin-like growth factor (IGF)-system mRNA quantities are higher in normal and tumor breast tissue of women with sporadic and familial breast cancer risk than in low-risk women.
According to recent research published in the journal Breast Cancer Research and Treatment, "The insulin-like growth factor (IGF)-system plays a role in breast cancer susceptibility as well as in growth and progression of breast carcinomas. So far, findings have been based on serum IGF-I levels and semi-quantitative assessment of IGF-system expression levels in model systems and human tissue. Quantitative data on mRNA expression in different ...