Article: Reduced allopregnanolone levels during luteal phase may contribute to PMS.

2004 JUN 3 - (NewsRx.com & NewsRx.net) -- A study comparing various hormone levels between women with premenstrual syndrome (PMS) those without suggests impaired production of allopregnanolone during the luteal phase of the menstrual cycle may contribute to the mood disorders PMS patients experience.

"Several studies have been performed during recent years to investigate the existence of a possible endocrine cause for premenstrual syndrome; the results reported are often discordant. Great interest has been raised around allopregnanolone, which could be involved in the determination of mood disorders reported by PMS patients. During the luteal phase, lower levels ...

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