Article: Galileo Genomics Discovers More Than 10 New Gene Candidate Regions in Crohn's Disease in Whole Genome Study Powered by Perlegen Technology.

MONTREAL, QUEBEC, AND MOUNTAIN VIEW, CALIFORNIA, June 22 /PRNewswire/ -- Galileo Genomics and Perlegen Sciences today announced the completion of a linkage disequilibrium-based genome-wide scan (LD-GWS) of Crohn's disease in the Quebec Founder Population.

The study identified two previously reported disease genes, NOD2/CARD15 and OCTN, and more than 10 new regions strongly associated with Crohn's disease, each containing one to four genes. The LD-GWS was performed on 1,500 individuals using more than 248,000 SNP markers distributed throughout the human genome, resulting in 372 million genetic analyses. This is one of the largest disease gene discovery surveys ...

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