Phenazopyridine hydrochloride (Pyridium[R], Azo-Standard[R], Urogesic[R], Uristat[R]) is an azo dye which is used as a urinary tract antiseptic and analgesic. The drug was initially marketed in the United States in 1914 as treatment for urinary tract infection (UTI), and it was widely believed to have bactericidal properties until the 1930s. In the 1940s, the first antibiotics were introduced and offered more effective and curative treatment for UTI. However, phenazopyridine is still often used as brief adjuvant therapy for treatment of UTI. Additionally, the drug is used for a number of urologic problems involving dysuria. Since a nonprescription dose is available, ...