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Article: Hearing loss mediated by T cells specific for inner ear peptides.
- Article from:
- Immunotherapy Weekly
- Article date:
- August 4, 2004
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2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Murine autoimmune hearing loss is mediated by CD4+ T cells specific for inner ear peptides.
According to published research from the United States, "Autoimmune sensorineural hearing loss (ASNHL) is characterized typically by bilateral, rapidly progressive hearing loss that responds therapeutically to corticosteroid treatment. Despite its name, data implicating autoimmunity in the etiopathogenesis of ASNHL have been limited, and targeted self-antigens have not been identified. In the current study we show that the inner ear-specific proteins cochlin and beta-tectorin are capable of targeting experimental autoimmune hearing ...