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Article: DNA immunization achieved with plasmids expressing hCG beta-chimeras.
- Article from:
- Biotech Week
- Article date:
- August 18, 2004
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2004 AUG 18 - (NewsRx.com & NewsRx.net) -- DNA immunization was achieved with plasmids expressing hCG beta-chimeras.
According to recent research from England, "Human chorionic gonadotropin has been used as an anti-fertility vaccine and as a target for cancer immunotherapy. We have explored the use of DNA immunization with the aim of improving the immunogenicity of this hormone. Stimulating the muscle with electric pulses following intramuscular injection of plasmids expressing hCGbeta resulted in higher levels of human chorionic gonadotropin (hCG)-specific antibodies, which could be further enhanced following a protein boost with hCG mixed with adjuvant."
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