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Article: Noninvasive imaging may show telomerase promoter activity in humans.
- Article from:
- Obesity, Fitness & Wellness Week
- Article date:
- September 25, 2004
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2004 SEP 25 - (NewsRx.com & NewsRx.net) -- Noninvasive imaging may show telomerase promoter activity in humans.
"We have assessed the feasibility of positron emission tomography (PET) and ex vivo gamma-counting to measure the pattern of expression of telomerase promoter fragments in vivo," scientists writing in the journal Cancer Research report.
"Promoter fragments from either the RNA [human telomerase RNA (hTR)] or the catalytic components [human telomerase reverse transcriptase (hTERT)] of the telomerase genes were used to drive the expression of the sodium iodide symporter PET reporter gene in recombinant adenoviruses. Both promoter fragments ...