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Article: Lymphoreticular tissues play role in intestinal IgA immunity.
- Article from:
- Obesity, Fitness & Wellness Week
- Article date:
- September 25, 2004
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2004 SEP 25 - (NewsRx.com & NewsRx.net) -- Gut-associated lymphoreticular tissues play a role in antigen-specific intestinal IgA immunity.
According to a study from Japan, Korea, and the United States, "This study assessed the roles of the postnatal lymphotoxin-beta receptor (LTbetaR)-mediated signals in the gut-associated lymphoreticular tissues of mice for subsequent regulation of antigen-specific intestinal IgA responses. Blockade of LTbetaR-dependent events by postnatal administration of the fusion protein of LTbetaR and IgG Fc (LTbetaR-Ig) reduced both the size and numbers of Peyer's patches (PP) without influencing the PP micro-architecture. Interestingly, ...